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                 Biochemistry


 

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 State
 Standards
 for
 Biology

Vocabulary:

Subatomic particles:
  protons
  neutrons
  electrons
valence electrons
atom
element
molecule
ion
ionic bond
covalent bond
polar
nonpolar
hydrogen bond
cohesion
adhesion
surface tension
pH
acid/base
hydrogen ions
hydroxyl ions
solution
solvent
solute
organic
carbohydrate
carbon ring
monosaccharide
disaccharide
polysaccharide
starch
cellulose
glycogen
chitin
polymer
monomer
dehydration
    synthesis
lipid
fatty acid chain
saturated
unsaturated
polyunsaturated
triglyceride
phospholipid
waxes
steroids (sterols)
proteins
keratin
amino acids
enzymes:
  substrate
  catalyst
  active site
  denature
nucleic acid:
   RNA
   DNA

 

This concept map was made on Bubbl.us website in 10 minutes.  Easy. 
You should use it for your studies.

JEOPARDY Review Game ppt.


Article: Faster-than-Light Neutrinos???  Impossible! (?)
 
Also in this article: Hadrons and leptons? Baryons and mesons? Fermions and bosons?  Gluons, quarks, photons?  Yes, there's more than protons, neutrons, and electrons going on in an atom.....

Atoms:  
  A page about how they're built and how they behave...

The Element Song...

See the illustrations below for Ionic, Covalent, and Hydrogen Bonding

Read the standards for Biochemistry

 

   OVERVIEW OF BIOLOGICAL MOLECULES:
    Use this from class: print for your notes...


  Organic
 Molecules ppt.
(new)
   (note: Rx = "reaction")
 
Click on image. 
    Very good explanations about organic molecules; nice illustrations!

  


The primary organic molecule categories:

 1. Carbohydrates (see below)

         >  The scoop on Carbohydrates
 
       >  An even deeper scoop...

 2. Lipids

          > 
An activity on LIPIDS
          >  Read a student's blogspot on lipids

  
  

 3. Proteins

         >  All you need to know about Proteins 

           > Enzymes are proteins: (see below)

                   1. Enzyme Video clip....                
                        2.
Video 2...  
                        3.
YouTube Video...
                        4.
Animation
(illustrates specificity, reusing, and denaturing)
         
Enzymes are proteins.  They allow a chemical reaction to occur between atoms/molecules (they can either assist in combining them or separating them).  The enzyme is not affected and is re-used over and over.  Only ONE enzyme is made to do ONE type of reaction, though. For example: Lactase is an enzyme that splits Lactose (a disaccharide) into its two monosaccharides, galactose and glucose.  Some people lack this enzyme Lactase, therefore have trouble digesting lactose.  Watch THIS to see it in motion...
 


 
4. Nucleic Acids (RNA and DNA) (studied in a later unit)

 

 How do the caloric values of carbs, lipids, and proteins compare?  Look here...

Macronutrient (1g) Calories Kilojoules
Protein 4 16.7
Fat 9 37.7
Carbohydrate 4 16.7

 

 


The properties of water:

 

Cohesion, Adhesion, Surface Tension, and Polarity
 

All about pH  

Image: the pH scale   (see below)
 


  "Food Inc." is a documentary about how our food is grown, harvested, processed, and sold to us.  It is much different than it was in our grandparents' day.  To some people, it is a disturbing change.  Below is an interview with the maker of the documentary.

Watch the full episode. See more NOW on PBS.


 
 

 

Periodic Table of the Elements (including Bohr models),
showing the most common elements in biology.

Covalent Bonding (sharing valence electrons):

Polar Molecules (having (+) and (-) ends:

Ionic Bonding (giving/taking of valence electrons):


Hydrogen bonding
:
When the positive hydrogen end of a molecule
binds with the negative end of some other molecule or atom...
(This is what makes individual water molecules stick together like magnets.)

The pH scale, with common household items
Note: "Alkaline" means the same as "basic" or "base."

Notice on this chart how the OH- and H+ amounts are inversely proportional.

Enzyme "Lock and Key" model:

Enzymes save energy in getting a reaction started...

 

  

 

 

CARBOHYDRATES:


These are monosaccharides.  Notice, only one carbon ring is present
(where the ring bends is a C, except where the oxygen is).

 

Dicaccharides are two rings together:

 

Polysaccharides are huge chains of rings.  Examples:
Glycogen (animals) energy storage
Chitin (insects, some fungi) structure
Starch [amylose] (plants) energy storage
Cellulose (plants) structure

different polysaccharides structures

It is essential for students to understand that proteins, carbohydrates, and fats have important functions within the human body:

· Proteins are involved in almost every function in the human body. For example, they serve as the

basis for structures, transport substances, regulate processes, speed up chemical reactions, and

control growth.

     ○ Proteins are more important as a source of building blocks than as a source of energy.
        Proteins can function as an energy source only if there is a shortage of carbohydrates or lipids.

¨ When proteins are consumed, the bonds that hold the amino acids together are broken

during the process of digestion so that individual amino acids are absorbed into the

bloodstream through the walls of the intestines.

¨ The amino acids are carried by the blood stream to cells throughout the body where they

cross into the cells through the cell membrane.

¨ Once inside the cell, they are used as raw materials to make all of the proteins required by

the organism.

             ○ Because of their structures, proteins serve different functions. For example,

¨ Structural proteins are used for support such as connective tissue and keratin that forms

hair and finger nails.

¨ Transport proteins transport many substances throughout the body such as hemoglobin

which transports oxygen from the lungs to the other parts of the body to be used by cells

in cellular respiration.

¨ Hormone proteins coordinate body activities such as insulin which regulates the amount

of sugar in the blood.

¨ Contractile proteins help control movement such as proteins in the muscles which help

control contraction.

¨ Enzymatic proteins accelerate the speed of chemical reactions such as digestive enzymes

which break down food in the digestive tract.

 

· Carbohydrates are important as an energy source for all organisms and as a structural molecule in

many organisms.

○ Carbohydrates are a primary source of fuel for cellular respiration.

○ Carbohydrates are also used to store energy for short periods of time.

○ The carbon, hydrogen, and oxygen that compose carbohydrates serve as raw materials for the

synthesis of other types of small organic molecules, such as amino acids and fatty acids.

○ Some carbohydrates (such as cellulose) are used as structural material in plants.

¨ For most animals, foods that contain these carbohydrates are important as fiber which

stimulates the digestive system.

 

· Fats (lipids) are important to organisms for energy when carbohydrates are scarce since they are

the primary way to store energy.

○ Fats serve a variety of functions in humans, such as providing long-term energy storage,

cushioning of vital organs, and insulation for the body.

○ Fats also serve as a major component of cell membranes and are one of the raw materials

necessary for the production of some vitamins and hormones.

 

The energy stored in organic molecules determines its caloric value. Proteins, carbohydrates, and fats/lipids are three organic molecules with different structures and different caloric values based on those structures:

· Proteins are molecules composed of chains of amino acids.

○ Amino acids are molecules that are composed of carbon, hydrogen, oxygen, nitrogen, and

sometimes sulfur.

○ There are 20 amino acids that chemically bond in various ways to make proteins. Twelve of

these amino acids are made in the body; others must be consumed from foods such as nuts,

beans, or meat.

○ Although proteins are more important as a source of building blocks, amino acids may be

used by the body as a source of energy (through the process of cellular respiration), but first

they must be converted by the body to carbohydrates. This process does not happen as long

as there is a carbohydrate or lipid available.

As a source of energy, proteins have the same caloric value per gram as carbohydrates.

· Carbohydrates (sugars and starches) are molecules composed of carbon, hydrogen, and oxygen.

○ The basic carbohydrates are simple sugars (monosaccharides) such as glucose. These simple

sugars can bond together to make larger, complex carbohydrate molecules, for example starch

or cellulose.

○ Carbohydrates are important because they the main source of energy for the cell.

¨ When carbohydrates are synthesized during the process of photosynthesis, the plants or

other photosynthetic organisms use them as a source of energy or they are stored in the

cells.

¨ When complex carbohydrates are consumed, the process of digestion breaks the bonds

between the larger carbohydrate molecules so that individual simple sugars can be

absorbed into the bloodstream through the walls of the intestines.

* The bloodstream carries the simple sugars to cells throughout the body where they

cross into the cells through the cell membrane.

* Once inside the cells, simple sugars are used as fuel in the process of cellular

respiration, releasing energy which is stored as ATP.

○ The caloric value of carbohydrates is dependent on the number of carbon-hydrogen bonds. If

an organism has a greater supply of carbohydrates than needed for its energy requirements,

the extra energy is converted to fats and stored by the body.

· Lipids, including fats, are organic molecules composed of carbon, hydrogen, and oxygen.

○ Lipid molecules are made of two component molecules (glycerols and fatty acids) so they are

structurally different from carbohydrates. Fats/lipids have more carbon-hydrogen bonds than

carbohydrates.

○ Fats are important to organisms for energy when carbohydrates are scarce, but when there is

no shortage of food, stored fat accumulates.

¨ When fats are consumed, the molecules are broken down during the process of digestion

so that individual glycerol and fatty acid molecules are absorbed into the bloodstream

through the walls of the intestines.

¨ The blood stream carries the glycerol and fatty acid molecules to cells throughout the

body where the molecules cross into the cells through the cell membrane.

¨ Once inside the cell, glycerols and fatty acids are stored for later use or used as fuel for

cellular respiration if there are no carbohydrates available.

¨ The process of cellular respiration releases the energy that is held in the chemical bonds of

the glycerol and fatty acid molecules.

· Due to the structure and number of the carbon-hydrogen bonds that hold the different types of

molecules (proteins, carbohydrates, or fats) together, fats contain more energy (ATP) per gram

than carbohydrates or proteins, which explains why fats have a greater caloric value.